Medical treatment of hyperprolactinemia

Hyperprolactinaemia (sometimes called hyperprolactinemia) is characterized by the atypically high levels of luteotropin (also called prolactin) in the body. Luteotropin is a protein hormone produced by hypophysis, its main functions are closely tied to breast milk production and breast development during pregnancy.

Hyperprolactinaemia can cause lactorrhea, among many other issues. Additional symptoms for this disease include:

  • Oligomenorrhoea or amenorrhea;
  • Hirsutism;
  • Osteopenia;
  • Pituitary insufficiency;
  • Loss of libido;
  • Infertility.

Hyperprolactinaemia can also occur in men with gender-specific symptoms including gynecomastia, impotence, and low body/facial hair. This disease is usually diagnosed via blood tests, vision test, or neuroimaging.

There are two distinct ways of treating hyperprolactinaemia – medication and surgery.

Drugs can oftentimes help to shrink the tumor, curb the luteotropin production, and eradicate symptoms. Usually, a dopamine receptor agonist is prescribed to treat hyperprolactinaemia. Frequently prescribed drugs are Bromocriptine and Cabergoline. It should be noted that the latter has a generic version with the same properties and cheaper price, you can even order buy generic Dostinex via the internet.

If medication wasn’t sufficient in curing hyperprolactinaemia, a patient will have to undergo a surgery to remove the tumor. Sometimes a surgery is required to alleviate pressure on the optical nerves. There exist two types of surgery:

  • Transsphenoidal surgery. Leaves no noticeable scars, compilation rates are almost non-existent. The tumour gets eliminated via the nasal passage.
  • Transcranial surgery. If the tumour is big or enough or has already affected adjacent brain tissue, a patient might require transcranial surgery.

The success rates for both of these surgeries are comparably high, sometimes both ways of treating hyperprolactinaemia are used in conjuncture. The third option for people that don’t respond to both medical and surgical treatment is radiotherapy.